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High Purity pharmaceutical raw material Enzyme Pepsin powder in Bulk
Pepsin is an acidic protease. Its inactive zymogen precursor, pepsinogen, is produced in the stomach mucosa. There are several pepsins designated A, B, C, and D. Pepsin A, the major component, has a molecular weight of 35,000 daltons and an optimum pH of approximately 1.0 for substrates such as casein or hemoglobin if the substrate is native protein. Pepsin cleaves proteins preferentially at carboxylic groups of aromatic amino acids such as phenylalanine and tyrosine. It will not cleave at bonds containing valine, alanine or glycine. Pepsin is assayed based on the method of Anson J. Gen. Physiol., 22, 79 (1938) using hemoglobin as the substrate. Pepsin is unstable above pH 6.
Pepsin is a digestive enzyme; it is extracted from Pepsinogen under PH 1.5-5.0 and the pepsinogen is secreted by the stomach cell.Pepsin can decompose the solidified proteins into peptone by effect of stomach acid, but it can not go any further to amino acid. The best effective condition for pepsin is PH 1.6-1.8
High Purity pharmaceutical raw material Enzyme Pepsin powder in Bulk
Pepsin is widely used for the dyspepsia caused by over taking proteinic foods and lack of stomach proteinase caused by digestive hypofunction in the recovering period. It also has effect on curing chronic of atronic of atrophic gastritis, gastric,gastric cancer and malignant anaemia.
